關於「NLRP3 inhibitor」標籤，搜尋引擎有相關的訊息討論：

A phenotypic high-content, high-throughput screen identifies ...。

2021年7月28日 · Small molecule inhibitors of the NLRP3 inflammasome have the potential to decrease inflammation and inflammasome-mediated cell death. MCC950 ( ...。

Oridonin is a covalent NLRP3 inhibitor with strong anti ... - Nature。

2018年6月29日 · Here, we show that Ori is a specific and covalent inhibitor for NLRP3 inflammasome. Ori forms a covalent bond with the cysteine 279 of NLRP3 ...。

Identification of a selective and direct NLRP3 inhibitor to treat ... - NCBI。

MCC950 has shown strong NLRP3 inflammasome inhibitory activity and beneficial effects in several mice models of NLRP3-related diseases, but it does not ...： tw | tw。

Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome ...。

2014年9月10日 · Share on. Email; Facebook; Twitter; Linked In; Reddit; Wechat ... Moreover, GL inhibited NLRP3- and AIM2-activated ASC oligomerization, ...。

Discovery and characterization of small-molecule inhibitors of ...。

2021年3月26日 · Inflammasome-mediated sterile inflammation plays a central role in ... among all the NLRP3 inhibitors, and through computational docking, ...： tw | tw。

Pharmacological inhibition of the NLRP3 inflammasome reduces ...。

In this study, we investigated whether MCC950, a recently-identified inhibitor of NLRP3 activity, reduces blood pressure (BP), renal inflammation, ...： 。

Specific Inhibition of the NLRP3 Inflammasome as an ... - ATS Journals。

2019年5月16日 · Rationale: Cystic fibrosis (CF) pulmonary disease is characterized by chronic infection with Pseudomonas aeruginosa and sustained ...。

NLRP3 inhibition attenuates early brain injury and delayed cerebral ...。

2021年7月20日 · Further, we observed a decrease in apoptosis of neurons in mice treated with MCC950. NLRP3 inhibition also prevented middle cerebral artery ...。

Full article: Small molecule-driven NLRP3 inflammation inhibition ...。

2019年4月9日 · In addition, the small molecule kaempferol (Ka) protected mice against LPS- and SNCA-induced neurodegeneration by inhibiting NLRP3 inflammasome ...。

The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive ...。

2020年12月15日 · In this study, we used an APP/PS1 mouse model for AD, which confirms significant cognitive losses that are recovered in NLRP3-deficient mice, to ...